Finally, common terms with cut-off P value < 0.05 including “neurotrophin signaling pathway”, “cAMP signaling pathway”, “Toll-like receptor signaling pathway”, “Renal cell carcinoma” and “Estrogen signaling pathway” were identified as the most strongly enriched pathway clusters for DEGs using all procedures with potential responsibility in AML chemo-resistance based on KEGG (Table 4). The gene discussed is BDNF; the disease is hereditary clear cell renal cell carcinoma.