Several genes within these cataract-associated loci, including RARB, KLF10, DNMBP, HMGA2, MVK, BMP4, CPAMD8, and JAG1, represent potential candidates for the development of drug targets as previous work supports the relevance of these candidates to cataracts74–81 (Supplementary Data 14). This evidence concerns the gene HMGA2 and cataract.