We validated p32 protein expression by western blot analysis in murine GBM cells, patient-derived GBM83 glioma stem cell (GSC) and human established glioma cells (Supplementary Fig. 1e) and by confocal microscopy in a syngeneic and PDX GBM mouse model, confirming specific expression in tumors but not in normal brain tissue (Fig. 1b). Here, C1QBP is linked to central nervous system cancer.