The latency of GBM83 tumors is on average 20 days so three days after injection of the tumor cells (the presence of a lesion was confirmed by luciferase positive signal) mice received one dose (1 × 107 cells) of UT or p32 hCAR T cells (containing ~4 × 106 hCAR+ T cells) intratumorally and another dose intraventricularly (2.5 × 106 total T cells, ~1 × 106 CAR+) (Fig. 4c). Here, CXADR is linked to neoplasm.