Other low-TE genes include FAXDC2, STYX, and SHOC2 which are involved in the Ras/Raf/Mitogen-activated protein kinase/ERK Kinase (MEK)/Extracellular-signal-Regulated Kinase (ERK) cascade (Rodriguez-Viciana et al. 2006; Reiterer et al. 2013; Jin et al. 2016), commonly involved in viral infection, including that of coronaviruses (Kumar et al. 2018). This evidence concerns the gene SHOC2 and viral infectious disease.