TLX2 and neoplasm: The univariate analysis showed that sex, age, and tumor size had no significant effect on OS (P > 0.05); on the other hand, differentiation degree (P < 0.05), CEA (P < 0.05), T stage (P < 0.05), lymph node metastasis (P < 0.01), distant metastasis (P < 0.01), and NCX expression (P < 0.01) affected the OS of CC (Table 2).