For example, GAS2 is a regulator in the ovary during folliculogenesis and oocyte cyst breakdown [43]; AIG1 is induced by androgen and expressed at high levels in the ovaries [44]; SPTA1 might be related to oocyte maturation [65]; FSHR is expressed in granulosa cells that regulates proliferation of granulosa cell, maturation of follicular and production estrogen [46]; CERS3 is related to androgen production [66]. This evidence concerns the gene SPTA1 and cyst.