The VEGF signaling pathway has been identified as the major driver of tumor angiogenesis (Ferrara, 2002; Ferrara & Kerbel, 2005; Kerbel, 2008; Apte et al,2019), and upregulation of the soluble VEGF‐A ligand (often simply referred to as VEGF) is associated with a wide range of malignancies (Kut et al,2007). This evidence concerns the gene VEGFA and neoplasm.