Based on these results, we deduced that Xuebijing has therapeutic effects on patients with ARDS partly by regulating the immune cell/cytokine pathways, such as maintaining CD4+ and CD8+ T cell balance, inhibiting p75(NTR) signaling, inhibiting CXCR4 and LPA signaling, promoting FAS (CD95) signaling, and thus inhibiting the producing and releasing of cytokines and chemokines. This evidence concerns the gene CD8A and acute respiratory distress syndrome.