Notably, the reduction of complex-type N-glycans in our MS analysis of aged murine hearts corresponds with findings for mannosyl (α-1,3-)-glycoprotein β-1,2-N-acetylglucosaminyltransferase (Mgat1) KO mice, which develop dilated cardiomyopathy (Ednie et al., 2019). This evidence concerns the gene MGAT1 and dilated cardiomyopathy.