Loss or reduced RKIP expression is associated with poor prognosis in numerous cancer types including endometrial cancer, cervical cancer, bladder cancer, breast cancer, gastric cancer, thyroid cancer and gliomas (Eun et al., 2010; Kim et al., 2010; Escara-Wilke et al., 2012; Martinho et al., 2012; Lamiman et al., 2014; Farooqi et al., 2015; Zaravinos et al., 2018). This evidence concerns the gene PEBP1 and cancer.