Hence, functional enrichment analysis and prediction of differentially expressed genes were carried out using public databases, such as GO enrichment analysis and KEGG pathway analysis, and we found that differential expressions of circRNAs between the CRNwNP and control groups were related to “amoebiasis,” “salivary secretion,” “cell adhesion molecules (CAMs),” “cAMP signaling pathway,” “focal adhesion”, “adherens junction,” “TNF signaling pathway,” and others. Here, TNF is linked to amebiasis.