CXCR2 and nasopharyngeal carcinoma: Yoshizaki et al. (2001) observed that CXCR2 and CXCL8 are abundantly expressed in clinical samples of NPC (Horikawa et al., 2005). Lo et al. (2013) demonstrated that CXCR2 and CXCL8 are expressed in NPC cell lines and induce the growth of tumour spheroids.