FTO and Familial prostate cancer: The majority of studies (Söderberg et al., 2009; Castillo et al., 2012; Iles et al., 2013; Li et al., 2017) have shown a strong association between FTO and an increased risk of various types of cancer, including breast cancer, prostate cancer, kidney cancer, endometrial cancer, pancreatic cancers, lymphoma, and leukemia.