TP53 and amebiasis: Kyoto Encyclopedia of Genes and Genomes pathway showed that induced genes were involved in regulating Fanconi anemia pathway, p53 signaling pathway, cell cycle, spliceosome, ribosome biogenesis in eukaryotes, ECM-receptor interaction, amebiasis, RNA transport, focal adhesion, and phosphoinositide 3-kinase (PI3K)–Akt signaling pathway (Figure 2B).