PLXDC2 and Lymphatic Metastasis: The comparisons of PLXDC2 expression of lymphatic metastasis (high vs. low, N1-N3b of AJCC are considered to have metastasis, N0 is considered to have no metastasis) and proportion of positive lymph node (>50% vs. <50%, within the total lymph nodes removed during operation), according to the unpaired t test results, showed no significant difference (Figures 7D,E).