TNF and neoplasm: The results of in vivo studies, performed using WEHI-164 fibrosarcoma-bearing mice, show that nanoparticles functionalized with iso1 and TNF according to this strategy (1-Au/TNF) could induce tumor eradication in WEHI-164 fibrosarcoma-bearing mice more efficiently than nanoparticles lacking the iso1 targeting moiety (2-Au/TNF).