NR1H2 and hepatocellular carcinoma: The LXRβ degradation activity of the synthesized PROTACs was evaluated by western blot using HuH-7 human hepatoma cells, and it was found that the activity of VH032-based PROTACs (GW3965-PEG-VH032) was more potent than that of pomalidomide-based PROTACs (GW3965-PEG-POM) between the PEG3-PEG5 linkers.