As shown in Figure 6A, comparing HCC tissues with normal tissues, we found that there were significant differences in 16 immune cells, including memory B cells, plasma cells, CD8 T cells, naive CD4 T cells, active CD4 memory T cells, follicular helper T cells, regulatory T cells, resting NK cells, active NK cells, monocytes, M0 macrophages, M1 macrophages, M2 macrophages, resting mast cells and neutrophils (Figure 6A). Here, CD4 is linked to hepatocellular carcinoma.