METTL18 and hepatocellular carcinoma: To better analyze the role of METTL18 in progression of HCC, we applied RNA-seq data from the TCGA and GEO datasets, with statistical and bioinformatics ways, such as differentially expressed genes (DEG) analysis, Kaplan–Meier (KM) survival analysis, and Cox & Logistic regression analysis, nomogram, Gene Ontology (GO) analysis, Gene Set Enrichment Analysis (GSEA), single-sample Gene Set Enrichment Analysis (ssGSEA).