On the other hand, the H3K27M mutation that has been highly linked to paediatric thalamic gliomas and is associated with a worse prognosis than low-grade tumours were not found in the TCGA cohort, which is the case of other biomarkers used in clinical studies, such as H3G34R, H3G34N, EGFR R776C, and the TERT promoter mutations C228T and C250T [23,24,31]. This evidence concerns the gene TERT and neoplasm.