Driver genes of tumorigenesis shared between GMB and the hsa:0513 pancreatic cancer pathway are BRAF, EGFR, SMAD3, PIK3CA, TP53, IDH1, TERT, VIM, ATRX and GFAP. Owing to their high proliferative condition, cancer cells have an increased demand for nutrients. This evidence concerns the gene SMAD3 and familial pancreatic carcinoma.