To improve the cancer-targeted efficiency, Anilkumar et al. constructed dual targeted magnetic photosensitive liposomes (MPLs) to deliver ICG to tumor tissues driven by a magnetic field and to internalize drugs into cells via the combination of HA and CD44.95 In this study, citric acid-coated Fe3O4 magnetic NPs (CMNs) and ICG molecules were loaded in MPLs via a solvent evaporation/hydration technique, and then HA-PEG was connected by electrostatic interaction triggered self-assembly to fabricate HA-PEG-MPLs. The gene discussed is CD44; the disease is cancer.