In terms of interaction with serious complications in COVID‐19 patients, 6 markers (MFAP4, ECM1, CDKN2B.AS1, CAPN2, FGG, and CD147) and 2 exRNAs (SNORD33 and miR‐122‐5p) are involved in thrombosis or liver injury. The gene discussed is ECM1; the disease is COVID-19.