HMOX1 and Parkinson disease: Recent in vitro and in vivo findings have demonstrated that FA exhibited increased levels of protective HO-1 activity in SH-SY5Y cells, upregulated the levels of CAT, SOD, GPx, and GSH, and reduced the lipid peroxidation level in MPTP-injected PD mouse models, which confirms FA's potential antioxidant effects in the prevention of PD [230].