Indeed, experimental studies showed that AA treatments increased striatal DA levels and upregulated striatal TH, TLR4, BDNF, and GFAP expression, subsequently decreasing striatal upregulation of α-synuclein, apoptotic markers, and Bcl-2 expression in MPTP-induced PD-like neurotoxicity in mice. Here, BCL2 is linked to Parkinson disease.