Some studies have found that [18] scalp acupuncture can increase the concentration of cytokines IL-1 β, TNF-α, and IL-6 in the brain tissue of insomnia rats; some studies have found that [16] scalp acupuncture may affect the secretion of neurotransmitters and regulate the central organs that affect sleep wakefulness; some studies [36] have found that using scalp acupuncture to stimulate insomnia's areas of interest to varying degrees can promote the balance of physiological functions of the cerebral cortex and regulate the autonomic nervous system. This evidence concerns the gene IL6 and insomnia.