SHOX and skeletal dysplasia: Alterations in SHOX expression impairs human growth and causes a spectrum of clinical phenotypes related to skeletal dysplasia and short stature including Léri-Weill dyschondrosteosis, Langer mesomelic dysplasia, Turner syndrome, and idiopathic short and tall stature (Rao et al., 1997; Belin et al., 1998; Shears et al., 1998; Oliveira and Alves, 2011; Fukami et al., 2016; Marchini et al., 2016; Monzani et al., 2019).