Interestingly, some immune or cancer-associated pathways belonged to the high-risk groups, including autoimmune thyroid disease, chemokine signal pathway, complement and coagulation cascade, leukocyte and transendothelial migration, nod-like receptor signal pathway, ECM receptor interaction, JAK-STAT signal pathway, MAPK signal pathway, melanoma, and pathway in cancer (Figures 11A–J). The gene discussed is SOAT1; the disease is autoimmune thyroid disease.