S100A2 and neoplasm: By and large, the protein expression level were consistent with the previous bioinformatics analysis: the protective genes (ADIPOR1, ARRB1, CD1B, KL, and VIPR1) were highly expressed in paracancer tissues compared with tumor tissues, while the remaining genes (HAMP, HMOX1, S100A12, S100A7, S100A2, TUBB3, and VEGFA) were more obvious in adenocarcinoma tissues.