Circulating VEGF levels were significantly higher in BD than in HC (SMD 1.65, 95% CI 0.88–2.41, P <0.0001) (Figure 5A) as well as in active BD than in inactive BD (SMD 0.91, 95% CI 0.26–1.55, P = 0.0064) (Figure 5B). The gene discussed is VEGFA; the disease is Behcet disease.