In IBD (Figure S11), circulating VEGF level exhibited a positive, poor correlation with Crohn’s disease activity index (CDAI; ES 0.34, 95% CI 0.10–0.57, P = 0.0053, summary r = 0.33), medium correlation with UC activity index (UDAI; ES 0.57, 95% CI 0.29–0.86, P = 0.0001; summary r = 0.52), strong correlation with ESR (ES 0.87, 95% CI 0.63–1.12, P <0.0001; summary r = 0.70), and weak correlation with platelet count (ES 0.32, 95% CI 0.16–0.49, P = 0.0001; summary r 0.31). Here, VEGFA is linked to Crohn disease.