Chemokines and cytokines are jointly involved in the occurrence and development of these two inflammatory diseases, such as serum TNF-α, vascular endothelial growth factor, IL12, monocyte chemotaxis Protein 1, S100A8/A9 and significantly increased IL17A, which play a central role in the development of psoriasis and atherosclerosis. The gene discussed is IL17A; the disease is psoriasis.