Atherosclerosis and psoriasis have many overlapping inflammatory environmental factors, including local and systemic immune processes, inflammatory cytokines/chemokines, such as serum TNF-α, vascular endothelial growth factor, IL12, monocyte chemotaxis Protein 1, S100A8/A9 and significantly elevated IL17A, etc. (3). The gene discussed is S100A8; the disease is atherosclerosis.