Chemokines such as IL-8/CXCL8 and proinflammatory cytokines such as IL-6 (p<0.05) and TNFα (p<0.05) were increased 1.4-, 4.7-, and 1.3-fold, respectively, in the plasma of patients with critical COVID-19, in comparison with patients with mild disease (Figure 1A). The gene discussed is TNF; the disease is COVID-19.