Although, the glucose tolerance was lower compared to age-matched non-diabetic naïve mice, glucose clearance of both control (n=1) and TGF-β1 PLGA particle treated (n=3) groups was efficient, with a return to normoglycemia (<200 mg/dL) within 60 min (Figure 6D) and equivalent glucose clearance (p = 0.068, one-way ANOVA, classified as the area under the curve) (Figure 6D, inset). Here, TGFB1 is linked to glucose measurement.