As shown in Supplementary Tables 7 and 8, the clinicopathologic characteristics were comparable betweenwfi 2 frozen and FFPE HCC samples.Th1-orientation genes (INFg, TBX21 and IL12B) and Th17-associated genes IL17A were significantly upregulated in pTLS-high HCC tissues compared to those with pTLS-low, whereas the expression of IL12A was comparable between the groups. This evidence concerns the gene IL12A and hepatocellular carcinoma.