Using a scatterplot quadrant analysis (Figure 1C), samples from the early phases of dengue (day 1-3 and day 4-6) were generally positive in both the total NETs and MPO-H4K8Ac, K12Ac, K16Ac ELISA (NOX-independent NETs), suggesting that NETs were predominantly NOX-independently generated (16). The gene discussed is MPO; the disease is dengue disease.