CD8A and infection: Previous studies, especially those examining ECs, have focused on the role of the CD8+ CTL response in controlling infection (Koup et al., 1994; Borrow et al., 1994; Barker et al., 1998; Wilkinson et al., 1999; Betts et al., 2001; Migueles and Connors, 2001; Sáez-Cirión et al., 2007; Betts et al., 2006; Yan et al., 2013; Cartwright et al., 2016; Nishimura et al., 2017; Nguyen et al., 2019; McBrien et al., 2020a,b).