However, the significant decrease in SodD in G. p. gambiensis in GpSGHV infected flies was associated with a significant decrease in WigD, which might indicate a different molecular mechanism governing the interaction between the endosymbiont, the GpSGHV and the host, most likely due to the fact that the GpSGHV infection in G. p. gambiensis is different from that in G. f. The gene discussed is BAG4; the disease is infection.