The OR's were somewhat attenuated upon addition of BMI but both the L/A ratio and in particular adiponectin, remained significantly associated with an elevated TC/HDL and TG/HDL ratio, also after further adjustment with other cardio-metabolic risk factors (i.e., CRP, smoking, HOMA-IR, DDD for AP), mood stabilizers, duration of illness, and duration of AP treatment to the models. The gene discussed is ADIPOQ; the disease is alkaline phosphatase measurement.