The immunohistochemical staining results showed that the Fibronectin, IL-1β and TNF-α were increased in the DCM group compared with the control group, but the protein expression levels of Fibronectin, IL-1β and TNF-α were reduced by YAP gene silencing in the LV-YAP-shRNA group (Figures 4H–J,L–Np < 0.05). Here, TNF is linked to familial dilated cardiomyopathy.