After understanding the post-translational modification (phosphorylation) of proteins (Figures 6A,B), KEGG pathway analysis noted that there were a large number of down-regulated phosphorylated proteins a/ggregating in multiple cascades, including Spliceosome, RNA transport, Leishmaniasis, Ribosome biogenesis, IL−17 signaling pathway, Salmonella infection and other signaling pathways after TMP treatment. This evidence concerns the gene IL17A and leishmaniasis.