TNF and inflammatory bowel disease: In line with the results of network pharmacological analysis, HYJJ down-regulated UC-related inflammatory pathways, such as IBD and TNF, NOD-like and Toll-like receptor signaling pathways, and facilitated salivary and pancreatic secretion, glutamatergic and dopaminergic synapse, fat digestion and absorption, all of which were mentioned in network analysis about the individual roles of HYJJ.