HMGA2 and neoplasm: As a tumor suppressor or tumor promoter, miR-let-7b has been found to halt cell proliferation, adhesion, and invasion by targeting Protein Code Gene (PKA1), Diaphanous Related Formin 2 (DIAPH2), Radixin (RDX), RAS, MYC, and High Mobility Group A2 (HMGA2) genes and their respective proteins.