CD40LG and Mental deterioration: The aMCI group showed that higher baseline levels of IL-2 (r = 0.420, p = 0.041), sCD40L (r = 0.419, p = 0.041), IL-8 (r = 0.410, p = 0.047), and VEGF (r = 0.491, p = 0.017) were significantly correlated with a lower cognitive decline.