P2RX7 and myeloid sarcoma: Despite the evidence that P2X7 receptors are widely expressed in both hematopoietic-derived and CNS resident immune cells (Collo et al., 1997; Yiangou et al., 2006; Hanley et al., 2012), knowledge is scarce regarding P2X7 receptor signaling in immune cells during inflammation processes of MS pathology.