Despite all three SCLC cell lines demonstrating suppression of NETFs after KRASG12V induction, YAP1 was significantly upregulated only in H82-KRASG12V cells treated with doxycycline for 7 days (3.3-fold, Supplementary file 1), which was mirrored by the weakly detectable YAP1 protein level in the same cell line by western blot (Figure 1—figure supplement 2g). Here, YAP1 is linked to small cell lung carcinoma.