HRAS and small cell lung carcinoma: However, in contrast to a previous study where the cell lines representing the classic subtype of SCLC, which are currently classified as SCLC-A (Rudin et al., 2019), showed no discernible phenotypic changes in response to HRAS expression (Mabry et al., 1988), we found that H2107 SCLC-A cells also demonstrated this phenotypic transition (Figure 1d and e).