HRAS and small cell lung carcinoma: Consistent with the results shown in previous reports (Falco et al., 1990; Calbo et al., 2011) in which HRAS or RASV12 were retrovirally transduced in SCLC cell lines, the SCLC-N cell lines both demonstrated a phenotypic transition from a suspended to adherent state after KRASG12V induction, with the most striking change occurring in H82 cells (Figure 1c–e).