INS and diabetes mellitus: Prevalence rates of IO vary widely depending on the methodology used, but studies using the Diabetes Eating Problem Survey-Revised (DEPS-R; Markowitz et al., 2010), a questionnaire considered one of the most psychometrically robust methods currently available in assessing insulin manipulation, have reported prevalence as high as 60.2% in a sample of individuals with T1D aged 13–55 years (Deiana et al., 2016).