Consistently, Alox5 specific inhibitors zileuton and 2,3,5‐trimethyl‐6‐(12‐hydroxy‐5,10‐dodecadiynyl)‐1,4‐benzoquinone (AA861), significantly inhibited proliferation and induced apoptosis of gastric cancer cells (Figure 5A and 5B). The gene discussed is ALOX5; the disease is gastric cancer.