IL6 and atherosclerosis: Previous studies demonstrated that several biomarkers were significantly associated with the pathogenesis of CAD: inflammatory response such as high-sensitivity C-reactive protein (hsCRP) [2] and interleukin-6 (IL-6) [3]; lipid metabolism such as triglyceride-rich lipoprotein-cholesterol (TRL-C) [4] and low-density lipoprotein cholesterol (LDL-C) [5]; hypercoagulability such as d-dimer [6] and fibrin degradation products (FDPs) [7]; atherosclerosis such as myeloperoxidase (MPO) [8], coronary artery calcium (CAC) [9] and phosphorus [10].