In addition, one sporadic case and one familial deletion of SOCS1 have been reported in multisystem inflammatory syndrome in children (MIS-C) from the United States.93) One patient developed a severe acute respiratory syndrome after SARS-CoV-2 infection, suggesting that SOCS1-deficiency may be related to the severity or prognostic symptoms of COVID-19. Here, SOCS1 is linked to COVID-19.