In the Tanzania study, we reported a significant association between methylation in IGF2/H19 imprinted domain and risk of CIN (OR: 1.51 95%CI:1.00–2.50) and ICC (OR: 2.00 95%CI:1.14–3.44) [16]. The gene discussed is H19; the disease is cervical squamous intraepithelial neoplasia.