Mice in the periodontitis + anti-G-CSF group also showed improvements in bone volume/total volume (Fig. 3G), bone surface area/bone volume (Fig. 3H), trabecular thickness (Fig. 3I), trabecular spacing (Fig. 3K), and trabecular pattern factor (Fig. 3L) values, compared with mice in the periodontitis group (P < 0.05). Here, CSF3 is linked to periodontitis.