IFNG and hepatocellular carcinoma: In the present study, we observed that, although the total NK cell proportion was rather higher in patients with BCLC BCD than in those with BCLC A HCC (P = 0.046), the total IFN-γ producing NK cell proportion was significantly lower in patients with BCLC BCD than in those with BCLC 0 (P = 0.045), and a trend of lower IFN-γ producing NK cell proportion was observed in patients with BCLC BCD than in those with BCLC A (P = 0.080).